BCCDC-PHL / tbprofiler-nf

Nextflow Wrapper for TBProfiler
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Coverage summary #12

Closed dfornika closed 5 months ago

dfornika commented 9 months ago

Generate a depth-of-coverage summary for each isolate, including:

...and possibly also

dfornika commented 9 months ago

It would probably make sense to tie the depth threshold to our existing min_depth parameter:

https://github.com/BCCDC-PHL/tbprofiler-nf/blob/f87175235b642d48cd03db5908b67c7902761037/nextflow.config#L21

dfornika commented 9 months ago

A couple of tools that might be useful:

https://github.com/brentp/mosdepth

https://telatin.github.io/bamtocov

taranewman commented 9 months ago

This tool looks like it can produce a .bed file showing only low-coverage regions: https://github.com/telatin/covtobed

dfornika commented 5 months ago

Fixed by #13 and #14