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BIMSBbioinfo
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pigx_bsseq
bisulfite sequencing pipeline from fastq to methylation reports
https://bioinformatics.mdc-berlin.de/pigx/
GNU General Public License v3.0
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Consider option to add spike-in genome for calculation of bisulfite conversion rate
#185
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alexg9010
opened
2 years ago
alexg9010
commented
2 years ago
I guess there are multiple options how this could be achieved:
add extra spike-in genome fasta file and perform extra round of mapping
add spike-in genome sequences to main genome file and filter out after mapping which reads mapped to spike-in chromosomes
tell users to create another settings file and perform another run
I guess there are multiple options how this could be achieved: