BIMSBbioinfo / pigx_rnaseq

Bulk RNA-seq Data Processing, Quality Control, and Downstream Analysis Pipeline
GNU General Public License v3.0
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add megadepth for fast genome coverage computation #102

Closed borauyar closed 2 years ago

borauyar commented 2 years ago

Keep deepTools::bamCoverage, but make megadepth the default.

So, setting megadepth as the default (most users) and keeping bamCoverage as an alternative could address all issues about flexibility, memory consumption, speed.

borauyar commented 2 years ago

Maybe consider bamToCov instead (seems to be as fast as megadepth with less memory consumption): paper: https://www.biorxiv.org/content/10.1101/2021.11.12.466787v1.abstract?%3Fcollection= code: https://github.com/telatin/bamtocov

borauyar commented 2 years ago

megadepth is added to the pipeline; see https://github.com/BIMSBbioinfo/pigx_rnaseq/commit/557bae8febb631e7aed3487b545ed15e10ba1e25