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BUStools / bustools

Tools for working with BUS files
https://bustools.github.io/
BSD 2-Clause "Simplified" License
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Question on Multi-part barcode correction in bustools 0.43.0 #96

Closed JohnMMa closed 1 year ago

JohnMMa commented 1 year ago

This is a relatively simple question. The release notes for v0.43.0 states,

  • The onlist supplied to bustools correct can have multiple columns so that each component of the barcode is correct[ed] independently.

Given bustools correct corrects unitary barcodes (such as those from 10X) that are 1 Hamming distance from the whitelist, does that mean if a multi-part whitelist is provided (which is likely the case when using combinatorial indexing, such as Parse or Scale), each component is corrected to a maximum of 1 Hamming distance--e.g. for a 4-component barcode, there's a likelihood that a barcode can be corrected to up to 4 Hamming distances?

Yenaled commented 1 year ago

Yes, that is exactly correct.

JohnMMa commented 1 year ago

Thanks @Yenaled ! I will close this issue.