Closed stephanmg closed 2 months ago
What is inconsistent? The Susceptible -> Infected reaction is not reversible, right?
Susceptible_to_Infected
Rate Law for Susceptible_to_Infected_1
The kinetic function is marked as irreversible but at least one of its variables is labeled as product.
Is this forbidden in SBML? The interaction between susceptible + infected
causes susceptible -> infected
, not infected -> susceptible
, right?
Is this forbidden in SBML? The interaction between
susceptible + infected
causessusceptible -> infected
, notinfected -> susceptible
, right?
Ah, the interaction should be non-reversible true. So what about this message from COPASI/SBML validator? False-positive warning?
False-positive warning?
I'm not sure, but this is my guess -- maybe it's unusual to see direct positive-feedback with the product in the kinetic law.
I think the rate law should be susceptible + infected -> infected + infected
rather than susceptible -> infected
I think the rate law should be
susceptible + infected -> infected + infected
rather thansusceptible -> infected
Ah thanks, makes sense, done in #222 , where the problem is further modified to be a more reasonable parameter estimation problem.
Can this issue then be closed in light of additional fixes in #222?
Make Bertozzi's
Susceptible_to_Infected
consistent.