Benchmarking-Initiative / Benchmark-Models-PEtab

A collection of mathematical models with experimental data in the PEtab format as benchmark problems in order to evaluate new and existing methodologies for data-based modelling
BSD 3-Clause "New" or "Revised" License
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Bertozzi_PNAS2020: update to match Table 1 of paper #222

Closed dilpath closed 1 month ago

dilpath commented 2 months ago

Some details in #99

I also changed the problem to be a simple SIR model, instead of the reparameterized SIR, but the reparameterization parameters are used in the parameters table, s.t. users can compare their parameter estimates to Table 1 of the original publication. The reparameterization is implemented as an SBML initial assignment rule $\beta = \frac{R_0 \gamma}{N}$.

I also removed some features like lockdown events, since they are irrelevant for reproducing the figure in Table 1 but complicate the simulation.

The scripts were updated to use petab.v1 and support output from petab.Problem.to_files_generic.

Checklist for the submission of new PEtab problems

dilpath commented 1 month ago

This PR passes CI (see #228, which is branched off this).