Updated manual curation for misannotated genes

[Vedanth-Ramji]

• RSA2 was mapped to ARO:3004445. This mapping was changed in the ARO to ARO:3005440. db_harmonisation should pick this up, but temporarily the issue is resolved through manual curation.
• grdA_1_QJX10702 (in resfinder curation) & EstD (in resfinder & megares curation) were mapped directly to drug classes. They are now mapped to correct parent AROs. grdA_1_QJX10702 -> ARO:3007380 and EstD -> ARO:3000557

[luispedro]

Yes, this is now correct, Luis

On Mon, 24 Jun 2024, at 3:25 PM, Vedanth Ramji wrote:

@.**** commented on this pull request.

In CHANGELOG.md https://github.com/BigDataBiology/argNorm/pull/55#discussion_r1650356751:

@@ -10,6 +10,10 @@

Manual curation

• argannot_curation: (Tet)tetH:EF460464:6286-7839:1554 was incorrectly annotated as ARO:3004797 which is a beta-lactamase due to a loose RGI hit. This was manually curated to ARO:3000175. +- deeparg, megares, resfinderfg & sarg curation: ARO:3004445 -> ARO:3005440, this was due to a change in the ARO and the ARO number for the RSA2 gene changing. db_harmonisation must change to take this into account +> Incorrectly curated genes. Previously, they were directly mapped to drug classes. Correct parent ARO term has now been given.

I have changed the formatting now. Is it ok?

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