Closed snaketron closed 5 years ago
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The DESCRIPTION file for this package is:
Package: IgGeneUsage
Type: Package
Title: Differential gene usage in immune repertoires
Version: 0.99.0
Authors@R:
person(given = "Simo",
family = "Kitanovski",
role = c("aut", "cre"),
email = "simo.kitanovski@uni-due.de")
Description: Differential gene usage in immune repertoires such as B-cell and
T-cell receptor repertoires with Bayesian hierarchical models.
License: GPL (>=3) + file LICENSE
Depends:
methods,
R (>= 3.6.0),
Rcpp (>= 1.0.1)
Imports:
rstan (>= 2.18.2),
rstantools (>= 1.5.1),
reshape2 (>= 1.4.3),
LinkingTo:
BH (>= 1.69.0-1),
Rcpp (>= 1.0.1),
RcppEigen (>= 0.3.3.5.0),
rstan (>= 2.18.2),
StanHeaders (>= 2.18.1-10)
Suggests:
BiocStyle,
knitr,
rmarkdown,
testthat (>= 2.1.0),
ggplot2,
ggforce,
gridExtra,
ggrepel
Encoding: UTF-8
LazyData: true
NeedsCompilation: yes
SystemRequirements: GNU make
biocViews: DifferentialExpression, Regression, Genetics, Bayesian
BugReports: https://github.com/snaketron/IgGeneUsage/issues
RoxygenNote: 6.1.1
VignetteBuilder: knitr
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It sounds like the input data could be represented as a SummarizedExperiment and this representation should be supported for robustness and interoperability with other packages in the Bioconductor community.
Yes, I considered implementing this, however, I found the SummarizedExperiment object much more complex than the commonly expected input of IgGeneUsage -> simple table with counts.
I will nevertheless implement the additional interface for the Bioconductor users.
Best
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611e03d simple makevars.win, probably won't work
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7c6d772 SummarizedExperiment input explained via a special...
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Dear developers (@mtmorgan),
I am rethinking the idea of representing the input data of IgGeneUsage as SummarizedExperiment object, as this class is much more general (and thus complex) than the typical input of IgGeneUsage. I believe this would limit the usability of the package in the R-community.
To nevertheless help the Bioconductor community, I developed a short vignette explaining how to convert an existing SummarizedExperiment object into a proper input for IgGeneUsage.
Please let me know what you think about this. Otherwise, the package has passed all checks and I am looking forward to the next part of the review.
Best
A better approach is to adapt your interface to accept SummarizedExperiment, perhaps in addition to your alternative representation; while SummarizedExperiment is unfamiliar to the general R user, it is very widely used in the Bioconductor community. By writing an interface, you relieve the user of having to follow, perhaps in an error-prone way, the instructions that you would otherwise lay out in your vignette.
Received a valid push; starting a build. Commits are:
33f787a implemented SummarizedExperiment interface
Thank you for the suggestion. I implemented the additional interface.
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f00c73e dependencies minifix
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