bioc-issue-bot
commented
3 years ago Hi @Jfortin1
Thanks for submitting your package. We are taking a quick look at it and you will hear back from us soon.
The DESCRIPTION file for this package is:
Package: crisprScore
Version: 0.99.0
Date: 2021-06-18
Title: On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
Authors@R: c(
person("Jean-Philippe", "Fortin", email = "fortin946@gmail.com", role = c("aut", "cre", "cph")),
person("Aaron", "Lun", email = "infinite.monkeys.with.keyboards@gmail.com", role = c("aut")),
person("Luke", "Hoberecht", email = "lukehob3@gmail.com", role = c("ctb")))
Depends: R,
crisprScoreData
Imports:
basilisk (>= 1.3.5),
Biostrings,
reticulate,
stringr,
utils
Suggests:
BiocStyle,
knitr,
rmarkdown,
testthat
biocViews:
CRISPR,
FunctionalGenomics,
FunctionalPrediction
Description:
Provides R wrappers of several on-target and off-target scoring methods for CRISPR guide RNAs (gRNAs).
The following nucleases are supported: Cas9, Cas12a and enCas12a.
The available on-target cutting efficiency scoring methods are Azimuth, DeepHF, DeepCpf1 and enPAM+GB.
Both the CFD and MIT scoring methods are available for off-target specificity prediction.
The package also provides a Lindel-derived score to predict the probability of a gRNA to produce
indels inducing a frameshift for the Cas9 nuclease.
License: CC BY-NC-ND 4.0 + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.1.1
VignetteBuilder: knitr
StagedInstall: no
LazyData: TRUE
LiNk-NY
Jfortin1
nturaga
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