bioc-issue-bot
commented
1 year ago Hi @ChristofSeiler
Thanks for submitting your package. We are taking a quick look at it and you will hear back from us soon.
The DESCRIPTION file for this package is:
Package: spillR
Type: Package
Title: Spillover compensation for mass cytometry data
Version: 0.99.0
Authors@R: c(
person("Marco", "Guazzini",
email= "m.guazzini@student.maastrichtuniversity.nl",
role = c("aut", "cre"), comment=c(ORCID="0009-0007-8111-5772")),
person("Alexander G.", "Reisach" ,
email="alexander.reisach@u-paris.fr", role = "aut"),
person("Sebastian", "Weichwald",
email= "sweichwald@math.ku.dk", role = "aut"),
person("Christof", "Seiler",
email= "christof.seiler@maastrichtuniversity.nl", role = "aut"))
Description: Channel interference in mass cytometry can cause spillover
and may result in miscounting of protein markers.
We propose a method that skips the matrix estimation step and
work directly with the full bead distributions.
We develop a nonparametric finite mixture model,
and use the mixture components to estimate
the probability of spillover.
We implement this in an R package spillR using
expectation-maximization and logistic regression.
We design spillR to provide a model-based compensation
for mass cytometry data.
biocViews:
FlowCytometry,
ImmunoOncology,
MassSpectrometry,
Preprocessing,
SingleCell,
Software,
StatisticalMethod,
Visualization,
Regression
License: LGPL-3
Encoding: UTF-8
LazyData: false
Config/testthat/edition: 3
RoxygenNote: 7.2.3
Imports:
dplyr,
magrittr,
tibble,
tidyselect,
SummarizedExperiment,
S4Vectors,
stats,
CATALYST,
ggplot2,
tidyr,
spatstat.geom
Suggests:
knitr,
rmarkdown,
cowplot,
testthat,
BiocStyle
VignetteBuilder: knitr
jianhong
ChristofSeiler
lshep
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