Open dxd429 opened 2 days ago
Hi @dxd429
Thanks for submitting your package. We are taking a quick look at it and you will hear back from us soon.
The DESCRIPTION file for this package is:
Package: mist
Title: Differential Methylation Analysis for scDNAm Data
Version: 0.99.0
Depends: R (>= 4.3.0)
Authors@R:
person("Daoyu", "Duan", , "dxd429@case.com", role = c("aut", "cre"),
comment = c(ORCID = "0000-0002-3147-2006"))
Description: mist (Methylation Inference for Single-cell along Trajectory) is a hierarchical
Bayesian framework for modeling DNA methylation trajectories and performing differential methylation
(DM) analysis in single-cell DNA methylation (scDNAm) data. It estimates developmental-stage-specific
variations, identifies genomic features with drastic changes along pseudotime, and, for two
phenotypic groups, detects features with distinct temporal methylation patterns. mist uses Gibbs
sampling to estimate parameters for temporal changes and stage-specific variations.
License: MIT + file LICENSE
Encoding: UTF-8
biocViews: Epigenetics, DifferentialMethylation, DNAMethylation, SingleCell, Software
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
Imports:
BiocParallel,
MCMCpack,
Matrix,
S4Vectors,
methods,
rtracklayer,
car,
mvtnorm,
SummarizedExperiment,
SingleCellExperiment,
BiocGenerics,
stats
Suggests:
knitr,
rmarkdown
VignetteBuilder: knitr
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