Biomaker / Biomaker-Challenge-2017

Main respository for documentation related to the 2017 Biomaker Challenge
MIT License
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Thomas Masters (Skills: Cell biology and FRET-based assays) #7

Open jcmolloy opened 7 years ago

jcmolloy commented 7 years ago

Name: Thomas Masters (tam55)

Organisation and Department: CIMR, University of Cambridge (up until 31st May 2017)

What ideas, if any, do you already have in mind for the Biomaker Challenge

See Issue #8

I would like to work on a low cost biosensor which might for instance detect any of the following (but other targets would be fine):

  1. Live bacteria using e.g. CalceinAM
  2. Cancer biomarkers (such as specific proteins or phosphor-proteins) either -- Expressed on the surface of intact blood cells or metastatic cancer cells -- In cell lysates of tumour biopsies

This could potentially be achieved by low cost optics to detect specific analytes via FRET, combined with microfluidics to organise and even multiplex samples. Alternatively instead of microfluidics an automated scanning stage could be used to examine multiwell plates containing cells/tissues.

What would you like to learn? Electronics, combined with computer/hardware interface and control, potentially microfluidics

What can you teach people? Cell biology and FRET-based assays