Having trouble understanding the cell cell interaction table

BiomedicalMachineLearning / stLearn

A novel machine learning pipeline to analyse spatial transcriptomics data

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Having trouble understanding the cell cell interaction table #308

Closed QiuYue117 closed 2 months ago

QiuYue117 commented 4 months ago

hi! May I ask how do i interpret the columns of this result? I dont quite understand the difference between the significant column and the adjusted pvalue, how does it constitute to significant, and what does the adjusted pvalue mean?

Thank you so much!!

BradBalderson commented 2 months ago

n_spot_sig are the significant hotspots of ligand-receptor interactions, after adjusting p-values for multiple hypothesis testing (MHT). n_spots_sig_pval are the number of hotspots without the MHT correction (nominal p-values).