BlishLab / scriabin

Analysis of cell-cell communication at single-cell resolution
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Usage question #19

Open ndrubins opened 8 months ago

ndrubins commented 8 months ago

Hi and thanks for this great package.

I have more of a usage question. I have data from lung, from two ages, 4 samples for each (hence many cells). My goals are to find CCC programs between the various cell types and they change with age and I'm not sure what's the best scriabin usage for this purpose: do I analyze both age groups together? If so do I run FindAllInteractionPrograms where group.by refers to sample/celltype/age? Or do I analyze each age group separately and then somehow compare between them? If so do I run FindAllInteractionPrograms where group.by refers to sample/celltype? And how would I then compare between the two age groups?

Thanks a lot.