BoevaLab / FREEC

Control-FREEC: Copy number and genotype annotation in whole genome and whole exome sequencing data
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Improve slightly procedure for best ploidy detection #50

Open gladkia opened 5 years ago

gladkia commented 5 years ago

Hi @valeu,

First of all, thanks for your work on ControlFreeC :).

I found that it would be nice to let the user decide what should be the maximal difference between fractions of the genome explained to consider ploidy = 2 as best ploidy instead of ploidy = 4.

Also, I added the analogous code for the change from ploidy = 3 to ploidy = 2. Does it have sense from the biological perspective ?

I tested the changes on the exemplary data with slightly changed config_ctrl.txt. As the difference between the fractions of genome explained (ploidy = 4 - ploidy = 2) equals ~0.07 I was able to confirm that new code works as expected.

Best, Arek