search

Borealis-BioModeling / aurora-pkpd

Open Python Web App for Pharmcological Modeling and Analysis
BSD 2-Clause "Simplified" License
0 stars 0 forks source link

New page for drug combination and synergy analysis #6

Closed blakeaw closed 2 days ago

blakeaw commented 1 month ago

Develop and add a new page for analyzing drug combinations and synergy. This could include different metrics of drug synergy, such as combination index, and possibly analysis for the MuSyC framework (https://www.nature.com/articles/s41467-021-24789-z).

blakeaw commented 1 month ago

Note that there is a MuSyC web application: https://musyc.lolab.xyz/

However, I wonder if it is still maintained since it is out of the LoLab at Vandy.

blakeaw commented 2 weeks ago

Like with HT Cell proliferation, I think I'll add an external tools section and point users to the MuSyC web application for drug combo and synergy analysis rather than trying to implement a subset of those features here in the Aurora app, which will help me focus more on implementing the compartmental modeling and non-compartmental analysis features.

blakeaw commented 2 days ago

Addressed in PR https://github.com/Borealis-BioModeling/aurora-pkpd/pull/20