BridgesLab / CushingAcromegalyStudy

The source code for the cushing and acromegaly studies, currently ongoing
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Response Issue #4: Why only 7 patients were used #42

Closed davebridges closed 9 years ago

davebridges commented 9 years ago

It is neither clear why only 7 out of 9 patients were used for the study. In addition, the study lacks mechanistic studies and/or validations that confirms the direct action of GH on the analyzed genes.

davebridges commented 9 years ago

The missing two patients for whom we had phenotypic data but not RNAseq data were included in Figure 1 but not other analyses. This was described in the methods section:

These subjects corresponded to the patients described in Table 1, with the exception of subjects 29 and 31 (both acromegaly patients), which had clinical data but no RNAseq data.