BrooksLabUCSC / flair

Full-Length Alternative Isoform analysis of RNA
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Question about filter option in collapsing step #236

Open eprdz opened 1 year ago

eprdz commented 1 year ago

As it is stated in the documentation (https://flair.readthedocs.io/en/latest/modules.html#flair-collapse) the "ginormous" option in the filter parameter will remove transcripts that follow the characteristics of the comprehensive set + monoexonic isoforms. I have compared a GTF transcriptome file created using the default option with one generated with the "ginormous" option, and although there are some monoexonic transcripts that have been filtered out, I do not understand why other monoexonic isoforms have remained.

Thank you in advance! :)