search

COBREXA / COBREXA.jl

COnstraint Based Reconstruction and EXascale Analysis (in Julia)
https://cobrexa.github.io/COBREXA.jl/stable/
Apache License 2.0
9 stars 0 forks source link

Feature: CycleFreeFluxes #29

Closed stelmo closed 4 weeks ago

stelmo commented 5 months ago

https://academic.oup.com/bioinformatics/article/31/13/2159/195895

exaexa commented 5 months ago

implementation hint: try to re-use as much of the parsimonious tooling as possible (maybe we should rename those to something like 2stage or postprocessing or so)

exaexa commented 5 months ago

@stelmo hey this is actually "just" the linear parsimonious FBA but with extra boudns on the exchanges, right?

BUT since the exchanges in the FBA are kinda free-floating, the normal linear parsimonious FBA would basically provide a compatible and correct CFF solution as well, right?