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COMBINE-lab / pufferfish

An efficient index for the colored, compacted, de Bruijn graph
GNU General Public License v3.0
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PuffAligner significantly slower at mapping and thread usage is much less than specified when running with `--compressedOutput` #42

Open hermidalc opened 1 year ago

hermidalc commented 1 year ago

I've test both with --compressedOutput and without, and surprised how much slower align is when it is activated, writing of the compressed SAM file becomes a bottleneck to the entire command, and thread usage is much lower than what is specified. This is surprising as I haven't see writing to a compressed stream to cause such a bottleneck and change in performance with other tools.

hermidalc commented 1 year ago

It's much faster to not use --compressedOutput and pigz the SAM file afterwards. Then align uses all the threads that are specified and maps at a much faster speed