COMBINE-lab / simpleaf

A rust framework to make using alevin-fry even simpler
BSD 3-Clause "New" or "Revised" License
41 stars 3 forks source link

10x genomics FFPE chemistry #131

Open wangjiawen2013 opened 5 months ago

wangjiawen2013 commented 5 months ago

Hi, 10x genomics has developed new technique to detect spatial gene expression of FFPE (formalin-fixed paraffin-embedded) tissue. About 20,000 probes are used to quantify the transcriptome. Cellranger now use the 20,000 probes as reference to map the reads. How to process the data using simpleaf ? image