Rework simulation settings

[luyckxn]

In some cases, specific settings are needed to run a simulation.

The idea behind this ticket is to englobe all these settings into a settings object, that can be passed as 1 argument to the simulate method. This settings object (constructor Settings) can accept subgroups of settings:

• Hardware settings (-> see Hardware() ): options to run simulations in parallel
• Solver settings (-> see Solver() ): options to pass to the ODE solver (e.g. atol, rtol, etc.)
• NOCB settings (-> see NOCB() ): useful settings for switching to NOCB / LOCF mode for given variables

And more settings to come...

[mattfidler]

Hi @luyckxn

rxode2 is currently being submitted to CRAN, it should be accepted whenever CRAN wants to push it through.

I have a fix for nlmixr2est after that but right now CRAN binaries do not work 😦

[luyckxn]

Hi Matt,

Thanks for your message. I'm currently installing rxode2 from your GitHub repo for the CI test with GitHub actions and that works fine. Good luck with the submission process!

[mattfidler]

Thanks