Open ghost opened 7 years ago
You can use the Cancer Gene Census dataset.
"Frequent" mutation is a little tricky as there is some duplication in COSMIC. It would be easier to just record how many times a site has been recorded in COSMIC. The iSTOP-paper
project generates this dataset. So this can be easily added.
I think the gene annotation stuff (e.g. is a CGC tumor suppressor) is more appropriate for the website than for the package. However, iSTOP site annotation (e.g. observed in COSMIC) does make sense to include in the package.
It would also be nice to have a column which indicates whether the sgSTOP recapitulates a frequent mutation in cancer or a place to search for cancer genes only.