search

Clinical-Genomics / scout

VCF visualization interface
https://clinical-genomics.github.io/scout
BSD 3-Clause "New" or "Revised" License
152 stars 46 forks source link

ClinVar exclude categories #4992

Open dnil opened 3 weeks ago

dnil commented 3 weeks ago

Is your feature request related to a problem in the current program to new available techology or software? Please describe and add links/citations if appropriate.

The ClinVar variantS filter is currently a bit clunky with two somewhat hard to understand checkboxes, plus the dropdown. And it still does not allow negation (as in exclude all Benign calls), at least not while retaining inclusion of non-value entries.

Describe the solution you'd like A refactor, allowing exclusion filter without making the already hard feature worse.

Perhaps the quality level does not have to be a checkbox? While being more careful about the actual contents. It would be lovely to be able to filter on eg the majority of calls, ignoring a single "Conflicting interpretations" or "Uncertain significance" from 2010...

northwestwitch commented 2 weeks ago

I'm working on this one!

dnil commented 2 weeks ago

Super! Be careful with the clinical filter functionality, obviously. 😸