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CodingBash / FlyCAGE

A modern web tool to find genes with similar expression
https://flycage.herokuapp.com/
Apache License 2.0
3 stars 1 forks source link

Research and think of ideas for cluster analysis #71

Open CodingBash opened 7 years ago

CodingBash commented 7 years ago

Perhaps we can take each gene in the gene set, and see and do objective or subjective analysis.

Objectively, we can create an evaluation formula to see the different in correlation r-vals between the genes in the gene set

Subjectively, we can create an evaluation formula to see how spread the genes in the gene set rank among other genes in the genome.

CodingBash commented 7 years ago

While gene set enrichment finds functional annotations of gene sets, what CAGE does is use the functional annotations (and other biological information) to create gene sets. A way we can verify the success of our tool is take the top results and feed them into a gene enrichment tool, and see if the results are significant.