ComparativeGenomicsToolkit / Comparative-Annotation-Toolkit

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[Enhancement] Diamond prescreen before exonerate #173

Open fbemm opened 4 years ago

fbemm commented 4 years ago

This is just to drop the idea. Tools like maker or funannotate pre-screen protein databases against the genome with diamond before starting to generate exonerate alignments only for significant pairings. Especially useful with larger protein files (e.g., SwissProt). Would be a nice thing to have. I can work on a PR, but this will take a while.

ifiddes commented 4 years ago

I can try to find time to do this; the protein component of this pipeline were definitely an afterthought and need to be more thoroughly vetted.