A PLM server instance is based on a custom domain-specific object model, which is similar to graph databases and ontologies.
The data model we developed for biomedical PLM applications, the Biomedical Imaging Lifecycle Management model, is very
general, because it needs to accommodate different modalities of data, such as imaging, clinics and bioinformatics. We have
successfully transformed this model to a core ontology for biomedical studies (BMSLM) [35]. For the PACIFIC-PRESERVED study,
we extended the existing general PLM model and core ontology with specific classes for the data types and variables of the
cardiology domain (echography, elastography, cardiac MRI, devices, etc.). All these elements were organized thematically
according to the Medical Subjects Heading concept tree. This process resulted in a data dictionary in ontological format,
named the PACIFIC ontology [36].
CONNECTED: leveraging digital twins and personal knowledge graphs in healthcare digitalization
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