DaehwanKimLab / hisat2

Graph-based alignment (Hierarchical Graph FM index)
GNU General Public License v3.0
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Recommended options for bacterial RNA-seq #178

Open apredeus opened 6 years ago

apredeus commented 6 years ago

Hello,

I was wondering if you would have any suggestions as to what options would be recommended for a bacterial RNA-seq. While regular genomic aligners are often used with bacterial data, they don't have the best compatibility with other RNA-seq specific tools, and limit some downstream options.

Right now I'm trying to come up with good settings for bacterial alignment, but don't have a very good idea how to benchmark the results. Any hints would be appreciated.