Memory Requirements to run alignment

DaehwanKimLab / hisat2

Graph-based alignment (Hierarchical Graph FM index)

GNU General Public License v3.0

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Memory Requirements to run alignment #348

Closed YasirKusay closed 2 years ago

YasirKusay commented 2 years ago

Hi,

How much RAM does HISAT2 require to align against its index? Does it load the entire index in memory or does it load them bit by bit? I am asking this because I would like to know how much RAM I will need to align against a very large index (the NT index, which is around 1500 GB).