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DiltheyLab / HLA-LA

Fast HLA type inference from whole-genome data
GNU General Public License v3.0
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Pre-computed index graph #72

Open BioinformaNicks opened 2 years ago

BioinformaNicks commented 2 years ago

Hi, small and perhaps stupid question:

In order to make HLA-LA feasible for low hardware setups - is it possible to transfer a pre-computed graph index (i.e. prepared on a HPC or server) to another machine? The 40GB Ram requirement makes it unfeasible on a standard machine, but it would be interesting if this would work?

Kind regards,

Nick

AlexanderDilthey commented 11 months ago

Hi @BioinformaNicks,

I think this may work if the two machines run similar hardware architectures and operating systems - the serialization of the index relies on the Boost library, and I am not sure under which circumstances the resulting serialized files are transferable.

I would recommend you try it out, and if you could post the results of the test here, this would also be great!

Best wishes

Alex