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DiseaseOntology / HumanDiseaseOntology

Repository for the Human Disease Ontology.
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Gastric cancer classification #423

Closed mikelivstone closed 3 years ago

mikelivstone commented 6 years ago

Requesting the following new terms per this reference:

Also note additional classification terms at that source.

lschriml commented 6 years ago

Thank you Mike !!

On Tue, Nov 28, 2017 at 2:47 PM, mikelivstone notifications@github.com wrote:

Requesting the following new terms per this reference http://www.cancer.ca/en/cancer-information/cancer-type/stomach/grading/?region=on :

  • "gastric cancer, intestinal type" (and mention Lauren classification system). Also, by inference, "gastric adenocarcinoma, intestinal type" as a sister of the existing term "gastric diffuse adenocarcinoma."
  • "gastric cancer, diffuse type" (and mention Lauren classification system)

Also note additional classification terms at that source.

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melodyswen commented 4 years ago

Diffuse type is reflected in DOID:6217 gastric diffuse adenocarcinoma but further work is needed to determine whether reorganization of gastric adenocarcinoma is needed (intestinal type and diffuse type)

melodyswen commented 4 years ago

Mike's link mentions the Lauren classification and the WHO classification system for stomach cancer. I am unsure about how to figure what to incorporate into DO

The World Health Organization (WHO) classification goes into more detailed groups than the Lauren classification. There are 5 main types of stomach cancer in the WHO classification.

tubular adenocarcinoma – This is made up of different sized small branching tubes (tubules). papillary adenocarcinoma – This tumour grows outward from the stomach wall and contains finger-like growths that stick out into the stomach cavity. The cells tend to look and behave much like normal cells. mucinous adenocarcinoma – There is a lot of mucin (the main substance in mucus) outside of the cancer cells. poorly cohesive carcinomas (including signet ring cell carcinoma and others) – These are arranged into clumps of cancerous cells. mixed carcinoma – This contains a mix of types of adenocarcinomas of the stomach.

DO already has gastric tubular adenocarcinoma, gastric papillary adenocarcinoma, which are part of the WHO classification.

lschriml commented 3 years ago

reviewed info in DO, as DO follows the WHO classification. No updates needed.