Vascular Parkinsons or Vascular Parkinsonism

[lschriml]

Could you add an entry for "Vascular Parkinsons" or "Vascular Parkinsonism". This would be a child of secondary Parkinsons syndromes. You have the cortical variant (vascular dementia) already listed DOID:8725, and vascular Parkinsons is a reasonably common post mortem diagnosis in the differential of Parkinsons disease.

Chris Lambert

[lschriml]

• vascular Parkinsonism added to the DO.

Notes:

movement disease (DOID:480) parkinsonism is defined as bradykinesia (slowness of movement) in combination with at least one between rest tremor (4–6 Hz) and rigidity

• Disturbances of balance, gait and posture

• Gait disturbances, balance and postural impairments https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578144/

  • vascular Parkinsonism

           - also known as lower body parkinsonism, is dominated by postural instability and 
           a broad-based gait disorder caused by vascular white matter lesions in patients  
            with a vascular risk profile.
       -  the parkinsonian features are of vascular origin 

    • symmetrical lower-body parkinsonism with gait unsteadiness and absence of tremors and is usually associated with pyramidal signs.
      • characterized by predominant lower-body parkinsonism, postural instability, shuffling or freezing gait, absence of rest tremor, absent or poor response to dopamine, and presence of corticospinal tract signs
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327701/