Mikado is a lightweight Python3 pipeline whose purpose is to facilitate the identification of expressed loci from RNA-Seq data * and to select the best models in each locus.
Sometimes transcripts are classified as open even when there is a methionine clearly downstream of the imputed start. We have to move the thick_start downstream in those cases.
if the ORF is legitimately open, we should change the phases of the transcript accordingly.
Issues we need to solve: