Elisseeff-Lab / domino

A software package for connecting cell level features in single cell RNA sequencing data with receptor ligand activity. Please be aware that an improved package, dominoSignal, is available.
https://fertiglab.github.io/dominoSignal/
GNU General Public License v3.0
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Running Domino with results from SCENIC R package #18

Open bhavyaac opened 2 years ago

bhavyaac commented 2 years ago

Hello,

Thank you for your great work on this package. In your documentation for Domino, you recommend the use of pySCENIC as it is a faster implementation of SCENIC, which is also available as an R package. I have used your package with pySCENIC outputs and it works smoothly.

I am planning to use Domino with some samples for which I have SCENIC results already, but from the R package and not from pySCENIC. I wonder if there is a way to call create_domino() with the output files of the SCENIC R package directly. I have noticed that the files are generally different formats, and the R package output generally looks like this example: https://scenic.aertslab.org/scenic_paper/examples/SCENIC_MouseBrain/output/

Please let me know if you have any advice for this. Thank you!