Ensembl / postgap

Linking GWAS studies to genes through cis-regulatory datasets
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Error with some rsIDs #180

Open jcmarca opened 2 years ago

jcmarca commented 2 years ago

Postgap fails when using specific variations in a summary file

Here is an example of a summary file including one of the failing rsID:

variant_id beta p-value rs2862954 -0.0291 2.00E-10

And this is the error message shown in the log file:

~/postgap/lib/postgap/Finemap.py:803: RuntimeWarning: divide by zero encountered in log return subset_sizenumpy.log(p) + (m - subset_size)numpy.log(1-p) ~/postgap/lib/postgap/Finemap.py:803: RuntimeWarning: invalid value encountered in double_scalars return subset_sizenumpy.log(p) + (m - subset_size)numpy.log(1-p) ~/postgap/lib/postgap/Finemap.py:803: RuntimeWarning: invalid value encountered in multiply return subset_sizenumpy.log(p) + (m - subset_size)numpy.log(1-p)

dzerbino commented 2 years ago

Hello @jcmarca ,

I hope you are doing well!

Could you please confirm which commit you are working off at the moment?

Cheers,

Daniel

jcmarca commented 2 years ago

Hi Daniel.

I’m doing well, thank you. I hope you are fine too.

I’m working in the Master branch updated until the last commit.

Commit f82a3ad7edcbffa9a99c1acbb2115e2363848e52 "Bump ipython from 6.2.1 to 7.16.3 in /tests”

Best, Jose.

On 3 May 2022, at 19:57, Daniel Zerbino @.***> wrote:

Hello @jcmarca https://github.com/jcmarca ,

I hope you are doing well!

Could you please confirm which commit you are working off at the moment?

Cheers,

Daniel

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