NTRs: medical exposures EPR/UDN surveys

[laurenechan]

Medical exposures (all communicable/external from the body exposures)

• [x] exposure to blood transfusion(s)
• [ ] exposure to shared hypodermic needles
• [ ] exposure to non-sterile needles
• [ ] exposure to a sexually transmitted infection
• [ ] exposure to chlamydia (chlamydia trachomatis)
• [ ] exposure to gonorrhea (Neisseria gonorrhea)
• [ ] exposure to genital herpes (herpes simplex 2)
• [ ] exposure to human papillomavirus (HPV), genital warts
• [ ] exposure to Trichomoniasis
• [x] exposure to anesthetics (including desflurane, enflurane, halothane, isoflurane, methoxyflurane, nitrous oxide, and sevoflurane)
• [ ] chicken pox/varicella
• [ ] Cold sores (Herpes simplex 1)
• [ ] Cryptosporidiosis (Crypto, parasitic diarrhea, chroptosporidium)
• [ ] Dysentery (shigellosis)
• [ ] flu (influenza)
• [ ] Food poisoning, bacterial (E Coli Enteritis)
• [ ] Food poisoning, viral (norovirus)
• [ ] German measles (Rubella)
• [ ] Hepatitis A
• [ ] Hepatitis B
• [ ] Hepatitis C
• [ ] HIV/AIDS, human immunodeficiency virus
• [ ] Legionnaires' Disease, legionellosis, legionella pneumophilia
• [ ] Lyme Disease, lyme borreliosis
• [ ] malaria, plasmodium
• [ ] measles, rubeola
• [ ] meningitis (bacterial, hemophilus influenza)
• [ ] meningitis (vital, enterovirus)
• [ ] Mononucleosis, mono, Epstein-Barr
• [ ] Mumps, paramyxovirus
• [ ] Pneumonia (bacterial, streptococcus pneumonia, hemophilus influenza)
• [ ] Pneumonia (viral, flu virus, respiratory syncytial virus, cold virus, rhinovirus)
• [ ] rocky mountain spotted fever, riskettsia riskettsia
• [ ] salmonella infection, salmonellosis
• [ ] shingles, herpes zoster
• [ ] staph infection, staphylococcus aureus
• [ ] streptococcal invasive disease, streptococcal pneumonia
• [ ] syphilis, treponema pallidum
• [ ] tuberculosis, TB, mycobacterium tuberculosis
• [ ] ulcers, helicobacter pylori
• [ ] whooping cough, pertussis
• [ ] exposure to hashimoto's disease
• [ ] exposure to excessive high fevers
• [ ] exposure to HPV vaccine (gardasil)
• [ ] exposure to kawasaki disease

Oncology exposures: (EPR, all non-communicable for the most part, modeled in mondo?) Exposure to any of the following cancer types (primary or secondary diagnosed cancer)

• [ ] bladder
• [ ] blood
• [ ] bone
• [ ] brain
• [ ] breast, including ductal carcinoma in situ
• [ ] cervix/cervical
• [ ] colon
• [ ] esophagus/esophageal
• [ ] gallbladder
• [ ] kidney
• [ ] larynx/windpipe
• [ ] leukemia
• [ ] liver
• [ ] lung
• [ ] lymphoma/Hodgkin's disease
• [ ] Non-Hodgkin's lymphoma
• [ ] melanoma
• [ ] mouth/tongue/lip
• [ ] spinal cord
• [ ] ovary/ovarian
• [ ] pancreas/pancreatic
• [ ] prostate
• [ ] rectum/rectal
• [ ] skin (non-melanoma)
• [ ] skin (don't know what kind)
• [ ] soft tissue (muscle or fat)
• [ ] stomach
• [ ] testis (testicular)
• [ ] throat/pharynx
• [ ] thyroid
• [ ] uterus/uterine Also of note (all of these are likely modeled in MAxO, although w/o context of cancer)
• [ ] surgery for cancer
• [ ] chemotherapy for cancer
• [ ] radiation for cancer
• [ ] hormonal therapy for cancer
• [ ] any other therapy for cancer

Female reproductive history terms (within mondo, HPO, MAxO, DRON, OMIT, VO)

• [ ] pregnancy (how many, includes: live, still birth, miscarriage, abortion, tubal or ectopic pregnancy)
• [ ] hypertension/high BP w/ pregnancy
• [ ] preeclampsia or toxemia
• [ ] diabetes or high blood sugar
• [ ] problems with placenta (abruptio placentae, placenta previa, other)
• [ ] intra-uterine growth restriction
• [ ] births (how many) **
• [ ] hysterectomy
• [ ] ovary removal
• [ ] menopause
• [ ] contraceptives
• [ ] hormone replacement medications
• [ ] endometriosis
• [ ] polyps in endometrium or uterus
• [ ] fibroids, fibroid tumors, uterine fibroids, or other benign uterine tumors
• [ ] ovarian cysts or benign ovarian growth or neoplasm

Male reproductive history: (Mondo, HPO, MAxO)

• [ ] enlarged prostate or benign prostatic hyperplasia
• [ ] inflammation of the prostate or prostatitis
• [ ] inflammation of epididymitis
• [ ] twisted testicle or testicular torsion
• [ ] abnormal location of a testicle
• [ ] sperm abnormalities
• [ ] abnormal veins near testis or varicocele
• [ ] produced a pregnancy
• [ ] infertility/ difficulty achieving pregnancy
• [ ] surgery on testicles

Other personal health reports: Height, weight, birth weight, premature birth, twin/multiple **, personal rating of health

Cardiovascular: ERP health and expo survey page 3 (Mondo, HPO for all categories)

• [ ] high blood pressure, hypertension
• [ ] high cholesterol
• [ ]atherosclerosis
• [ ]cardiac arrhythmia
• [ ]angina
• [ ] myocardial infarction
• [ ] coronary artery disease
• [ ] congestive heart failure
• [ ] peripheral artery disease, blocked or narrow arteries
• [ ] Raynaud's syndrome or disease
• [ ] pulmonary embolus
• [ ] balloon angioplasty, stent, bypass surgery
• [ ] transient ischemic attack
• [ ] stroke (ischemic, hemorrhagic, other)

Diabetes and Endocrine

• [ ] pre-diabetes
• [ ] diabetes
• [ ] exogenous insulin
• [ ] gestational diabetes
• [ ] oral blood glucose medication

Thyroid disease

• [ ] hyperthyroidism
• [ ] hypothyroidism
• [ ] enlarged thyroid or goiter
• [ ] benign growth nodule or tumor

Respiratory

• [ ] allergic rhinitis
• [ ] chronic obstructive pulmonary disease
• [ ] idiopathic pulmonary fibrosis
• [ ] tuberculosis (latent or active)
• [ ] breathlessness
• [ ] wheezing or whistling in chest
• [ ] asthma
• [ ] asthma attack
• [ ] asthma medication

Neurologic:

• [ ] seizure disorder or epilepsy
• [ ] migrane headaches
• [ ] Parkinson's disease
• [ ] Post traumatic stress disorder
• [ ] Alzheimer's disease
• [ ] Multiple sclerosis

Digestive

• [ ] celiac disease
• [ ] lactose intolerance
• [ ] Crohn's disease
• [ ] ulcerative colitis
• [ ] polyps in colon or rectum
• [ ] gallbladder disease
• [ ] stomach or duodenal ulcer
• [ ] cirrhosis
• [ ] fatty liver disease or steatosis
• [ ] hepatitis (A, B, C, unknown)

Renal

• [ ] chronic kidney disease
• [ ] end stage renal disease
• [ ] kidney stones
• [ ] pyelonephritis, nephritis or kidney infection
• [ ] polycystic kidney disease

Immune:

• [ ] allergies or allergic reactions
• [ ] scleroderma or systemic sclerosis
• [ ] shingles
• [ ] fibromyalgia
• [ ] Lupus or SLE or LE
• [ ] Sjogren's syndrome

Hematological

• [ ] hemochromatosis
• [ ] iron deficiency anemia
• [ ] pernicious anemia
• [ ] sickle cell disease

Bone, Joints, Muscles

• [ ] bone loss, thinning, osteopenia, pre-osteoporosis
• [ ] brittle bones or osteoporosis
• [ ] gout
• [ ] myositis
• [ ] rheumatoid arthritis
• [ ] osteoarthritis
• [ ] other type of arthritis

Skin, Eyes, and Hair:

• [ ] psoriasis
• [ ] eczema
• [ ] urticaria or hives
• [ ] keloids (after surgery, piercings, or skin injury)
• [ ] natural hair and eye colors **

Fatigue, feelings of being "run down" etc...

• [ ] chronic fatigue syndrome

Behavioral Health

• [ ] manic-depressive illness or bipolar disorder (or blood relatives diagnosed) Other questions in Health and Environment survey, page 9 discussing mood. We have other med info we can incorporate, HPO terms are available to describe these participants (UDN)

[diatomsRcool]

@matentzn we need to talk about exposure to diseases. Some of these surveys ask if someone has ever had cancer. It is not readily obvious to me how to do this or if we should.

[matentzn]

My intuition would be that the disease term should be used if a person was diagnosed with a disease; in some case exposure to a disease (like malaria) could be useful if the person did not actually contract the disease, but I cant really think of a real world use case (unless diagnosis status is unknown?). Lets discuss this at the next call!

[diatomsRcool]

Would "tumorectomy" MAXO_0001110 work for "cancer surgery"?

[laurenechan]

In response to @matentzn 's thoughts from a while ago, on the Mondo call yesterday it seemed as though Melissa was not interested in having any exposure to virus/viroid/organism/infectious agent terms in ECTO and she wanted to maintain the organism relationship axioms within Mondo. @diatomsRcool I think that could be a suitable word choice for some cancer surgeries, but I anticipate there are likely many different types of cancer surgery and we wouldn't be fully accurate to only list tumorectomy...