As a bioinformatician, I would like to calculate the average DNA methylation across a series of known DNA-associated protein binding footprint regions based on ChIP-seq experiments, using data from the LOLA package (ie the ENCODE and Codex data sets), in order to later find binding footprints associated with DMRs/conditions.
oneillkza
commented
6 years ago
Description
As a bioinformatician, I would like to calculate the average DNA methylation across a series of known DNA-associated protein binding footprint regions based on ChIP-seq experiments, using data from the LOLA package (ie the ENCODE and Codex data sets), in order to later find binding footprints associated with DMRs/conditions.
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@oneillkza has code which can be adapted for this