We’ve been asked to provide some guidance on how to describe animal models used in an in vivo study.
We’ve thought about different approaches ranging from a big compositional model to simply collecting the terms for each component part, for example:
A mouse (species) with a particular strain (could be described by MGI nomenclature: http://www.informatics.jax.org/mgihome/nomen/ and normalizing to other terminologies like “gene” modified, “disease” represented by the model and an observed “phenotype”
Simple would be best, we would prefer a simple “minimal” standard (or set of standards) that many people could use across many different in vivo labs.
We’ve been asked to provide some guidance on how to describe animal models used in an in vivo study. We’ve thought about different approaches ranging from a big compositional model to simply collecting the terms for each component part, for example: A mouse (species) with a particular strain (could be described by MGI nomenclature: http://www.informatics.jax.org/mgihome/nomen/ and normalizing to other terminologies like “gene” modified, “disease” represented by the model and an observed “phenotype”
Simple would be best, we would prefer a simple “minimal” standard (or set of standards) that many people could use across many different in vivo labs.
Owner: Dorothy Reilly (dorothy.reilly@novartis.com)