FRED-2 / OptiType

Precision HLA typing from next-generation sequencing data
BSD 3-Clause "New" or "Revised" License
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Bam file to prefilter reads #147

Closed SirKuikka closed 2 months ago

SirKuikka commented 3 months ago

Hi,

If I have already aligned my reads against the human reference genome, is it a good idea to first take reads with samtools that align to chr6 and alternative chr6 contigs, and HLA contigs. Then I wouldn't have to align the whole set of reads against the human reference genome, which takes longer

b-schubert commented 2 months ago

yes, that is recommended.