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FelixKrueger / Bismark

A tool to map bisulfite converted sequence reads and determine cytosine methylation states
http://felixkrueger.github.io/Bismark/
GNU General Public License v3.0
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Minimum conversion efficiency for filter_non_conversion #663

Closed gevro closed 3 months ago

gevro commented 3 months ago

Hi, Is there a minimum conversion efficiency below which filter_non_conversion will not be advisable or useful to use? For example is 95% conversion efficiency useful to use filter_non_conversion? Or 92.5%, or 90%? At some point, I assume it will not be advisable.

Thanks

FelixKrueger commented 3 months ago

I don't think there is a generally accepted 'minimum conversion efficiency', it really is more in the eye of the beholder.