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FlyBase / GO-curation

For projects related to GO curation in FlyBase
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CILIA/CILOGENESIS genes review #115

Open hattrill opened 2 months ago

hattrill commented 2 months ago

A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans PMID:37317646 https://pubmed.ncbi.nlm.nih.gov/37317646/

Looks like a good resource to make a larger gene group for Cilia-related genes. Already have these related groups:

AXONEMAL DYNEIN HEAVY CHAINS (DYNA) AXONEMAL INNER ARM DYNEIN HEAVY CHAINS (DYN-IAD) AXONEMAL OUTER ARM DYNEIN HEAVY CHAINS (DYN-OAD)

AXONEMAL DYNEIN INTERMEDIATE CHAINS (DYNA-IC) AXONEMAL INNER ARM DYNEIN INTERMEDIATE CHAINS (DYNIA-IC) AXONEMAL OUTER ARM DYNEIN INTERMEDIATE CHAINS (DYNOA-IC)

INTRAFLAGELLAR TRANSPORT COMPLEXES (IFT) BBSOME (BBS) INTRAFLAGELLAR TRANSPORT SUBCOMPLEX-A (IFT-A) INTRAFLAGELLAR TRANSPORT SUBCOMPLEX-B (IFT-B)

TRANSITION ZONE COMPONENTS (TZ) CEP290 COMPLEX (CEP290C) MKS COMPLEX (MKS) UNCLASSIFIED TRANSITION ZONE COMPONENTS (TZ-U)

Note: DYNEIN LIGHT CHAINS - are not divided into AXONEMAL and CYTOPLASMIC DYNEIN LIGHT CHAINS - are not divided into AXONEMAL and CYTOPLASMIC

hattrill commented 2 months ago

PMID: 38442096 Cep131-Cep162 and Cby-Fam92 complexes cooperatively maintain Cep290 at the basal body and contribute to ciliogenesis initiation