Open admclachlan opened 1 year ago
From Schlegel et al. (2024) - FBrf0260535:
In total, 7% of proposed hemibrain types were combined to define new ‘composite’ types (for example, SIP078,SIP080) because the hemibrain split could not be recapitulated when examining neurons from both FlyWire and the hemibrain (Fig. 3i and Extended Data Fig. 4e–g). This is not too surprising as the hemibrain philosophy was explicitly to err on the side of splitting in cases of uncertainty2. We found that 5% of proposed hemibrain types needed to be split, for example, because truncation of neurons in the hemibrain removed a key defining feature
I think we can go ahead now and merge the 'composite' types (with commas in 'hemibrain_type' in supplement 1)
I would like to see further supporting evidence (better descriptions of differences and more brains) before doing the splits - the existing hemibrain terms are good enough for now, without creating a bunch of new terms that might need to be obsoleted in future if not reproducible.
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