FlyBase / flybase-controlled-vocabulary

The home of the FlyBase miscellaneous ontologies - incorporating the Drosophila Phenotype Ontology (see also FlyBase/drosophila-phenotype-ontology)
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two new tool terms: children of reporter enzyme #221

Closed gm119 closed 2 months ago

gm119 commented 2 months ago

I think it would be good to add two new terms under the current 'reporter enzyme' term, so that users can easily distinguish reporters that use 'chemical tagging' (e.g. SNAP-tag, Halo-tag) or result in bioluminesence (e.g. luciferase).

here are my suggestions for the two new terms:

[Term] id: FBcv:NEW name: chemical labeling reporter namespace: experimental_tool_descriptor def: "Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme whose activity results in covalent tagging of the protein product with a small molecule whose properties (typically fluorescence) can be used to detect the presence of that protein product." [FBC:GM] subset: common_tool_use is_a: FBcv:0005005 ! reporter enzyme

[Term] id: FBcv:NEW name: bioluminescence reporter namespace: experimental_tool_descriptor def: "Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme whose activity results in bioluminescence, which can be used to detect the presence of that protein product." [FBC:GM] subset: common_tool_use is_a: FBcv:0005005 ! reporter enzyme

aoifelarkin commented 2 months ago

This seems like a good idea and the descriptions look clear to me. Should be useful for users.