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FoxoTech / methylize

Python-based Illumina methylation array analysis software
MIT License
14 stars 4 forks source link

add Variably Methylated Regions (VMR) to DMR pipeline #16

Open marcmaxson opened 3 years ago

marcmaxson commented 3 years ago

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210618/

DiffVar: a new method for detecting differential variability with application to methylation in cancer and aging Methylation of DNA is known to be essential to development and dramatically altered in cancers. The Illumina HumanMethylation450 BeadChip has been used extensively as a cost-effective way to profile nearly half a million CpG sites across the human genome.