Closed monicagerber closed 2 years ago
Hi @mayerbry, we talked about looking at recent publications so we can decide on the best name for the response magnitude. If you could point us to some links or make a suggestion, that'd be helpful. Thanks in advance!
I found two recent examples of clinical work with nab results and they use "ID50 Titer" or similar so I think we should stick with that. For pre-clinical work (and rare clinical work) there are background/control titers like MLV. This is not the standard case, but I think there should be a comment reminder that the titer calculation should be verified and explicitly defined if there is subtraction. The correct notation (ex, net ID50 titer or MLV-subtracted titer) for plots can be established per conversation with lead stat/lab under those circumstances.
Thanks, Bryan. This is helpful. I changed the methods to "ID~50~ titer" and added a note about MLV-subtracted titers to the top.
Hi @asatofh, please let me know if you approve these changes. Once you approve, I can merge this PR.
Thanks for reviewing the NAb template draft.
To create this draft, I reviewed:
Some notes:
Can you please complete this review by COB 1/20? Let me know if you need additional time. I may schedule a working meeting for us to review edits like we did with BAMA.
Thank you!