FroeseLab / crispr-ngs-pipline

A work-in-progress pipeline to identify cripsr off-target effects using somatic variant calling
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Add multiple groups per "patient" #1

Open votti opened 2 months ago

votti commented 2 months ago

For Crispr off target effects we need to do the variant calling for each sample to the parental cell line. I would propose to encode this in the units:

patient_id = parental cell line sample = normal (=reference) or other sample name

votti commented 2 months ago

Looking more into this: maybe it will be better to use https://nf-co.re/sarek/3.4.0 to begin with