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GEMINI-Medicine / Rgemini

A custom R package that provides a variety of functions to perform data analyses with GEMINI data
https://gemini-medicine.github.io/Rgemini/
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Investigate elixhauser imputation #72

Closed vaakesan-SMH closed 1 month ago

vaakesan-SMH commented 5 months ago

Currently when there are no diagnoses at admission, compute_charlson_comorbidity imputes 0 for these encounters.

Elixhauser comorbidity adopts the same approach although the lowest possible Elixhauser score is -20. However this distribution matches what we expect from the derivation paper:

image

If this is the correct imputation strategy, note this in the function documentation. Otherwise adjust the imputation strategy as needed.

vaakesan-SMH commented 4 months ago

In addition, the current citation in the documentation references a 1998 paper where Anne Elixhauser proposed the Elixhauser comorbidities:

Elixhauser A, et al. Med Care, 1998. https://doi.org/10.1097/MLR.0b013e31819432e5)

However the Elixhauser comorbidity index (the single numeric score) comes from van Walraven et al, 2009 (which is the paper linked in the DOI address).

Simply update the citation to reference van Walraven et al.