Clinical trials are often conducted in homogenous patient populations, but cancer therapies are administered to diverse populations. The outcomes described in clinical trials and risks of those outcomes may not be applicable to populations that were under-represented in the original trials. 10x will investigate a service that combines findings from published clinical trial regimens with original patient population demographics and their outcomes could power a risk calculator. Patients and providers could enter specific information about the patient and the service would calculate estimated risks for different therapies. This tool could help providers talk with patients and achieve shared decision-making on the most effective therapy considering patient choice and other quality of life outcomes. This project could use existing APIs and resources that hold information on published clinical trials, creating algorithms to estimate risk, and making an interface available to patients and providers.
An idea submitted by civil servants at:Department of Health and Human Services, National Institutes of Health
Clinical trials are often conducted in homogenous patient populations, but cancer therapies are administered to diverse populations. The outcomes described in clinical trials and risks of those outcomes may not be applicable to populations that were under-represented in the original trials. 10x will investigate a service that combines findings from published clinical trial regimens with original patient population demographics and their outcomes could power a risk calculator. Patients and providers could enter specific information about the patient and the service would calculate estimated risks for different therapies. This tool could help providers talk with patients and achieve shared decision-making on the most effective therapy considering patient choice and other quality of life outcomes. This project could use existing APIs and resources that hold information on published clinical trials, creating algorithms to estimate risk, and making an interface available to patients and providers.
An idea submitted by civil servants at: Department of Health and Human Services, National Institutes of Health