This was developed at the request of and sponsored by the department for Health Evidence of the Radboud UMC Nijmegen.
This PR implements the option --flipmaf for palinear, palogist and pacoxph, which will flip the reference and alternate alleles for MAF < 0.5. In cases of rare alleles, this can give better estimates of the betas.
This was developed at the request of and sponsored by the department for Health Evidence of the Radboud UMC Nijmegen.
This PR implements the option
--flipmafforpalinear,palogistandpacoxph, which will flip the reference and alternate alleles for MAF < 0.5. In cases of rare alleles, this can give better estimates of the betas.