When the user clicks on the question mark of the ~prevalence over time~ relative growth advantage plot, the component should be overlayed with an explanation text.
We can use this slightly adapted version of the text from CoV-Spectrum:
If variants spread pre-dominantly by local transmission across demographic groups, this estimate reflects the relative viral intrinsic growth advantage of the focal variant in the selected country and time frame. We report the relative growth advantage per [generation time] days (in percentage; 0% means equal growth). Importantly, the relative growth advantage estimate reflects the advantage compared to the co-circulating variants. Thus, as new variants spread, the advantage of the focal variant may decrease. Different mechanisms can alter the intrinsic growth rate, including an intrinsic transmission advantage, immune evasion, and a prolonged infectious period. When absolute numbers of a variant are low, the growth advantage may merely reflect the current importance of introductions from abroad or the variant spreading in a particular demographic group. In this case, the estimate does not provide information on any intrinsic fitness advantages.
Example: Assume that 10 infections from the focal variant and 100 infections from the co-circulating variants occur today and that the focal variant has a relative growth advantage of 50%. Then, if the number of new infections from the co-circulating variants remains at 100 in [generation time] days from today, we expect the number of new infections from the focal variant to be 15.
Reference:
Chen, Chaoran, et al. "Quantification of the spread of SARS-CoV-2 variant B.1.1.7 in Switzerland." Epidemics (2021); doi: 10.1016/j.epidem.2021.100480
When the user clicks on the question mark of the ~prevalence over time~ relative growth advantage plot, the component should be overlayed with an explanation text.
We can use this slightly adapted version of the text from CoV-Spectrum: